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MCQ on antibacterials: Page-3

Listed below are few of the drugs that act as antibacterials. Select the drugs that are metabolic enzyme inducers.

(A) Q,R and S

(B) P and S

(C) P,Q and R

(C) Q and R

Which of the following drug acts as a non-selective MAO-inhibitor

(A) Linezolid

(B) Clindamycin

(C) Vancomycin

(D) Quinupristin

Linezolid is an oxazolidinone which inhibits protein synthesis and also has weak MAO inhibitory activity. Hence it should be carefully given with food containing monoamines like tyramine otherwise results in cheese reaction.

Identify the drugs from the following that are considered as extended spectrum antibiotics

(A) R,S

(B) R

(C) Q

(D) P,Q

Ticarcillin and piperacillin are antipseudomonal penicillins. Ampicillin, amoxicillin and pivampicillin are extended spectrum penicillins. Clavulanic acid is a beta lactamase inhibitor. Among III generation cephalosporins, cefixime is an orally active and ceftazidime, cefotaxime and ceftriaxone are given parenterally.

The breakdown of imipenem is prevented by concomitant administration of

(A) Vancomycin

(B) Cilastatin

(C) Penicillins

(D) Cycloserine

Imipenem produces nephrotoxicity due to formation of toxic metabolite in renal tubules because of its breakdown in the kidney by dehydropeptidases. This enzyme is inhibited by co-administration with cilastatin hence nephrotoxicity can be prevented.

Select one of the glycopeptide antibiotic from the following

(A) Azithromycin

(B) Tobramycin

(C) Telavancin

(D) Vancomycin